UHPLC Column, RP C4 Butyl, 1.8um, 100A. 2.1mm ID x 150mm Length. Cogent Brand. 1 EA.
Additional Information:
Cogent RP C4 Butyl is a reversed-phase HPLC and UHPLC stationary phase designed for the separation of hydrophobic to moderately hydrophobic compounds. Manufactured using a traditional butyl (C4) bonded phase on ultra-high purity silica and fully double end capped, it provides reproducible retention, excellent peak shape, and reduced secondary interactions. The shorter alkyl chain offers less retention than C8 or C18 phases, making it well suited for fast analyses, biomolecules, peptides, proteins, and method development where excessive retention is undesirable.
68104-15P-2 is a UHPLC column packed with 1.8 µm RP C4 Butyl particles featuring a 100 Å pore size in a 2.1 mm ID x 150 mm format. The 150 mm length maximizes resolution and peak capacity for complex separations, while the 1.8 µm particle technology delivers exceptional efficiency and chromatographic performance. This column is specifically engineered for high-pressure UHPLC applications and is intended to take full advantage of UHPLC instrumentation capable of operating at the elevated pressures generated by sub-2 µm particles. Typical operating flow rates are approximately 0.2–0.4 mL/min. Because of the low flow rates required by 2.1 mm ID columns, any HPLC system used with this column must be capable of delivering accurate and reproducible low-flow performance.
Ideal for very hydrophobic and neutral compounds, this column provides maximum chromatographic efficiency, increased peak capacity, excellent resolution of complex mixtures, reduced solvent consumption, and enhanced laboratory productivity. The 2.1 mm ID format is particularly well suited for LC-MS applications. While compatible HPLC systems may be used for certain methods, this column is designed primarily for UHPLC operation where the full benefits of sub-2 µm particle technology—including superior efficiency, higher resolution, increased sensitivity, and faster separations—can be fully realized.
Key Benefits
RP C4 Butyl stationary phase
Fully double end capped
Traditional butyl bonded phase
Ultra-high purity silica support
Engineered for UHPLC applications
1.8 µm particle technology
Exceptional column efficiency
Increased peak capacity
Maximum chromatographic resolution
Reduced solvent consumption
Typical Applications
UHPLC analysis
High-pressure liquid chromatography
LC-MS methods
High-resolution separations
Method development
Peptide analysis
Protein analysis
Hydrophobic compound analysis
Neutral compound analysis
Pharmaceutical analysis
Specifications
Product Type: UHPLC Column
Stationary Phase: RP C4 Butyl
Chromatography Mode: Reversed Phase
Bonded Phase: Butyl (C4)
Endcapping: Fully Double End Capped
Particle Size: 1.8 µm
Pore Size: 100 Å
Column Dimensions: 2.1 mm ID x 150 mm
Length: 150 mm
Typical Flow Rate: 0.2–0.4 mL/min
Brand: Cogent
Important Notes
Specifically designed for UHPLC operation and high-pressure reversed-phase separations
Delivers maximum performance when used on a UHPLC system designed for sub-2 µm particle columns
May be used on compatible HPLC systems that can reliably operate at the required pressures and low flow rates
Sub-2 µm particles generate significantly higher backpressure than conventional HPLC columns
The 2.1 mm ID format is ideal for LC-MS applications and reduced solvent consumption
Standard HPLC systems must be capable of precise and reproducible operation at approximately 0.2–0.4 mL/min
The 150 mm length maximizes resolution and peak capacity for complex separations
Samples should be filtered through a 0.2 µm syringe filter prior to injection
Lower retention than comparable C8 or C18 stationary phases
Ideal when the highest chromatographic efficiency and resolving power are required